MolNFT v1 · #144850 · protein + RNA

Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex

6C6K: “Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex”. X-ray diffraction, 1 ligand (MG). MolNFT v1 #144850 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6C6K
Type: protein + RNA
Length: 1,020 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P09914, O14879
Ligands: MG

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	456	—	P09914
B	—	protein	454	—	P09914
C, D	—	protein	44	—	O14879
E, F	—	rna	11	—	—

Ligands and binding sites

MG · Magnesium ion · metal · 4 copies · chains B, F, A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6C6K · Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein… · the same entry in another collection · chain F against F, TM-score 1.00
P09914 · AlphaFold monomer V2.0 prediction for interferon-induced protein with tetratricopeptide… · a predicted model of the same protein · chain B against A, TM-score 0.99
O14879 · AlphaFold monomer V2.0 prediction for interferon-induced protein with tetratricopeptide… · a predicted model of the same protein · chain C against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09914
Every structure of UniProt O14879
Elsewhere: RCSB PDB 6C6K · PDBe 6C6K · UniProt P09914 · UniProt O14879

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