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MolNFT v1 · #144794 · protein

Human csrc SH3 domain in complex with choline kinase fragment 60-69

6C4S · Proto-oncogene tyrosine-protein kinase SRC,CSRC SH3 domain: “Human csrc SH3 domain in complex with choline kinase fragment 60-69”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #144794 on GenesisL1: 3D structure, binding sites and…

PDB
6C4S
Type
protein
Length
148 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Proto-oncogene tyrosine-protein kinase SRC,CSRC SH3 domain
EC
2.7.10.2
UniProt
P12931
Ligands
ZN

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 35% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BProto-oncogene tyrosine-protein kinase SRC,CSRC SH3 domain (EC 2.7.10.2)protein744% helix, 35% strandP12931

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 1108 Ų buried · 18 hydrogen bonds · protein-protein

Compared structures

  • 6C4S · Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69 · the same entry in another collection · chain A against A, TM-score 1.00

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