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MolNFT v1 · #144516 · protein

Hendra virus W protein C-terminus in complex with importin alpha 1

6BW1 · Protein W: “Hendra virus W protein C-terminus in complex with importin alpha 1”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #144516 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6BW1
Type
protein
Length
434 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein W; Importin subunit alpha-1
UniProt
P0C1C6, P52293
Pockets
1 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 73% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
CProtein Wprotein80% helix, 0% strandP0C1C6
EImportin subunit alpha-1protein42674% helix, 0% strandP52293

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1760.500.8413empty

Interfaces

1 interface between chains.

  • C–E · 692 Ų buried · 16 hydrogen bonds · protein-protein

Compared structures

  • 6BW1 · Hendra virus W protein C-terminus in complex with Importin alpha 1 · the same entry in another collection · chain C against C, TM-score 1.00

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