MolNFT v1 · #144515 · protein
Nipah virus W protein C-terminus in complex with importin alpha 1
6BW0 · Protein W: “Nipah virus W protein C-terminus in complex with importin alpha 1”. X-ray diffraction, 1 pocket (best druggability 0.47). MolNFT v1 #144515 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BW0
- Type
- protein
- Length
- 434 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein W; Importin subunit alpha-1
- UniProt
- P0C1C7, P52293
- Pockets
- 1 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Protein W | protein | 8 | 0% helix, 0% strand | P0C1C7 |
| E | Importin subunit alpha-1 | protein | 426 | 74% helix, 0% strand | P52293 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.47 | 0.83 | 12 | empty |
Interfaces
1 interface between chains.
- C–E · 696 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 6BW0 · Nipah virus W protein C-terminus in complex with Importin alpha 1 · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C1C7
- Every structure of UniProt P52293
- Elsewhere: RCSB PDB 6BW0 · PDBe 6BW0 · UniProt P0C1C7 · UniProt P52293
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