MolNFT v1 · #144508 · protein

Importin alpha 1 in cargo free state

6BVT · Importin subunit alpha-1: “Importin alpha 1 in cargo free state”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #144508 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6BVT
Type: protein
Length: 426 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin subunit alpha-1
UniProt: P52293
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
E	Importin subunit alpha-1	protein	426	74% helix, 0% strand	P52293

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.50	0.85	13	empty

Compared structures

6BVT · Importin alpha 1 in cargo free state · the same entry in another collection · chain E against E, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52293
Elsewhere: RCSB PDB 6BVT · PDBe 6BVT · UniProt P52293

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