MolNFT v1 · #144365 · protein

Structure of A6 reveals a novel lipid transporter

6BR9 · Protein A6 homolog: “Structure of A6 reveals a novel lipid transporter”. X-ray diffraction, 2 ligands (6OU, PGV), 3 pockets (best druggability 0.52). MolNFT v1 #144365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6BR9
Type: protein
Length: 233 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein A6 homolog
UniProt: Q9J563
Ligands: 6OU, PGV
Pockets: 3 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein A6 homolog	protein	233	78% helix, 3% strand	Q9J563

Ligands and binding sites

6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · ligand · 4 copies · chains A
PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	284	0.52	0.74	29	6OU
2	285	0.52	0.74	33	empty
3	186	0.46	0.74	23	empty

Compared structures

6BR9 · Structure of A6 reveals a novel lipid transporter · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9J563
Elsewhere: RCSB PDB 6BR9 · PDBe 6BR9 · UniProt Q9J563

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