MolNFT v1 · #144237 · protein
Human hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((R)-2-hydroxy-2-PHOSPHONOETHYL)OXY-1-N- (PHOSPHONOPROPIONYL)PYRROLIDINE
6BNJ: “Human hypoxanthine guanine phosphoribosyltransferase in complex with…”. X-ray diffraction, 2 ligands (WPG, MG). MolNFT v1 #144237 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BNJ
- Type
- protein
- Length
- 816 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00492
- Ligands
- WPG, MG
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 197 | — | P00492 |
| B | — | protein | 207 | — | P00492 |
| C | — | protein | 204 | — | P00492 |
| D | — | protein | 208 | — | P00492 |
Ligands and binding sites
- WPG · (3-{(3R,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-[(2R)-2-hydroxy-2-phosphonoethoxy]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid · ligand · 4 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 8 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6BNJ · Human hypoxanthine guanine phosphoribosyltransferase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00492
- Elsewhere: RCSB PDB 6BNJ · PDBe 6BNJ · UniProt P00492
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