MolNFT v1 · #144071 · protein
1.15 a resolution structure of norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor
6BID · 3C-like protease: “1.15 a resolution structure of norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor”. X-ray diffraction, 1 ligand (DW4). MolNFT v1 #144071 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6BID
- Type
- protein
- Length
- 173 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3C-like protease
- EC
- 3.4.22.66
- UniProt
- Q83883
- Ligands
- DW4
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3C-like protease (EC 3.4.22.66) | protein | 173 | 9% helix, 50% strand | Q83883 |
Ligands and binding sites
- DW4 · benzyl [(8S,11S,14S)-11-(cyclohexylmethyl)-8-(hydroxymethyl)-5,10,13-trioxo-1,4,9,12,17,18-hexaazabicyclo[14.2.1]nonadeca-16(19),17-dien-14-yl]carbamate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 6BID · 1.15 A resolution structure of Norovirus 3CL protease in complex with a triazole-based… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83883
- Elsewhere: RCSB PDB 6BID · PDBe 6BID · UniProt Q83883
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