MolNFT v1 · #144015 · protein

Caspase-3 mutant - S150D

6BGQ: “Caspase-3 mutant - S150D”. X-ray diffraction, 5 ligands (ACE, NA, AZI). MolNFT v1 #144015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6BGQ
Type: protein
Length: 488 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P42574
Ligands: ACE, NA, AZI, 0QE, CL

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	—	protein	146	—	P42574
B, D	—	protein	94	—	P42574
K, L	—	protein	4	—	—

Ligands and binding sites

ACE · Acetyl group · ligand · 2 copies · chains B, K, D, L
NA · Sodium ion · metal · chains C, D
AZI · Azide ion · ion · 10 copies · chains A, B, C, D
0QE · Chloromethane · ion · 2 copies · chains A, B, K, C, D, L
CL · Chloride ion · ion · 2 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6BGQ · Caspase-3 Mutant - S150D · the same entry in another collection · chain L against L, TM-score 1.00
P42574 · AlphaFold monomer V2.0 prediction for caspase-3 (P42574) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42574
Elsewhere: RCSB PDB 6BGQ · PDBe 6BGQ · UniProt P42574

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.