MolNFT v1 · #143477 · protein

Structural insights into the induced-fit inhibition of fascin by a small molecule

6B0T: “Structural insights into the induced-fit inhibition of fascin by a small molecule”. X-ray diffraction, 1 ligand (C7V). MolNFT v1 #143477 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6B0T
Type: protein
Length: 2,922 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q16658
Ligands: C7V

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F	—	protein	487	—	Q16658

Ligands and binding sites

C7V · 4-methyl-N-(1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indazol-3-yl)-1,2-oxazole-5-carboxamide · ligand · 6 copies · chains A, B, C, D, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6B0T · Structural Insights into the Induced-fit Inhibition of Fascin by a Small Molecule · the same entry in another collection · chain F against F, TM-score 1.00
Q16658 · AlphaFold monomer V2.0 prediction for fascin (Q16658) · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16658
Elsewhere: RCSB PDB 6B0T · PDBe 6B0T · UniProt Q16658

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