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MolNFT v1 · #143187 · protein

Filamentous assembly of green fluorescent protein supported by a C- terminal fusion of 18-residues, viewed in space group P212121 form 2

6AS9: “Filamentous assembly of green fluorescent protein supported by a C- terminal fusion of 18-residues, viewed in…”. X-ray diffraction, 1 ligand (PIA), 1 pocket (best druggability 0.74). MolNFT v1 #143187 on GenesisL1: 3D structure…

PDB
6AS9
Type
protein
Length
244 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Green fluorescent protein
UniProt
P42212
Ligands
PIA
Pockets
1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 48% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGreen fluorescent proteinprotein24418% helix, 48% strandP42212

Ligands and binding sites

  • PIA · [(4Z)-2-[(1S)-1-aminoethyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · ligand · chains A
  • ACT · Acetate ion · additive · 2 copies · chains A
  • MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1730.740.9822PIA

Modifications

Observed in the structure: 2 covalent (covalent ligand).

Compared structures

  • 6AS9 · Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of… · the same entry in another collection · chain A against A, TM-score 1.00
  • P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 0.93

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