MolNFT v1 · #143116 · protein
Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl) propane-1,2-DIYL]BIS(OXYETHANE-2,1-DIYL)}BIS(PHOSPHONIC acid)
6APT: “Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with…”. X-ray diffraction, 1 ligand (45T). MolNFT v1 #143116 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6APT
- Type
- protein
- Length
- 339 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07010
- Ligands
- 45T
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 169 | — | Q07010 |
| B | — | protein | 170 | — | Q07010 |
Ligands and binding sites
- 45T · {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl) propane-1,2-diyl]bis(oxyethane-2,1-diyl) }bis(phosphonic acid) · ligand · 2 copies · chains A, B
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6APT · Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q07010 · AlphaFold monomer V2.0 prediction for hypoxanthine-guanine phosphoribosyltransferase… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07010
- Elsewhere: RCSB PDB 6APT · PDBe 6APT · UniProt Q07010
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