MolNFT v1 · #143013 · protein + DNA
Structure of HIV-1 reverse transcriptase (rt) ternary complex with a double stranded DNA and an incoming D4TTP at pH 7.0
6AMO: “Structure of HIV-1 reverse transcriptase (rt) ternary complex with a double stranded DNA and an incoming…”. X-ray diffraction, 2 ligands (D4T, MG). MolNFT v1 #143013 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AMO
- Type
- protein + DNA
- Length
- 2,008 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- D4T, MG
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 555 | — | P03366 |
| B | — | protein | 412 | — | P03366 |
| T, E | — | dna | 22 | — | — |
| P, F | — | dna | 20 | — | — |
| D | — | protein | 402 | — | P03366 |
Ligands and binding sites
- D4T · 2',3'-dehydro-2',3'-deoxy-thymidine 5'-triphosphate · ligand · 2 copies · chains A, T, P, C, E, F
- MG · Magnesium ion · metal · 4 copies · chains A, C
- GOL · Glycerol · additive · 13 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6AMO · Structure of HIV-1 reverse transcriptase (rt) ternary complex with a double stranded DNA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 6AMO · PDBe 6AMO · UniProt P03366
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