MolNFT v1 · #142764 · protein
Tssl periplasmic domain
6AEO · MALTOSE/MALTODEXTRIN-binding periplasmic PROTEIN,TSSL: “Tssl periplasmic domain”. X-ray diffraction, 12 pockets (best druggability 0.65). MolNFT v1 #142764 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AEO
- Type
- protein
- Length
- 1,081 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MALTOSE/MALTODEXTRIN-binding periplasmic PROTEIN,TSSL
- UniProt
- P0AEY0, A0A1B3FDW3
- Pockets
- 12 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MALTOSE/MALTODEXTRIN-binding periplasmic PROTEIN,TSSL | protein | 541 | 43% helix, 21% strand | P0AEY0, A0A1B3FDW3 |
| B | MALTOSE/MALTODEXTRIN-binding periplasmic PROTEIN,TSSL | protein | 540 | 42% helix, 19% strand | P0AEY0, A0A1B3FDW3 |
Ligands and binding sites
- GOL · Glycerol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 701 | 0.65 | 0.74 | 69 | empty |
| 2 | 307 | 0.59 | 0.77 | 42 | empty |
| 3 | 238 | 0.54 | 0.76 | 31 | empty |
| 4 | 75 | 0.44 | 0.81 | 24 | empty |
| 5 | 79 | 0.42 | 0.79 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 391 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6AEO · TssL periplasmic domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEY0
- Every structure of UniProt A0A1B3FDW3
- Elsewhere: RCSB PDB 6AEO · PDBe 6AEO · UniProt P0AEY0 · UniProt A0A1B3FDW3
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