MolNFT v1 · #142686 · protein
Crystal structure of human vaccinia-related kinase 1 (VRK1) in complex with AMP-pnp
6AC9: “Crystal structure of human vaccinia-related kinase 1 (VRK1) in complex with AMP-pnp”. X-ray diffraction, 4 ligands (ANP, MG, SO4). MolNFT v1 #142686 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AC9
- Type
- protein
- Length
- 1,246 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q99986
- Ligands
- ANP, MG, SO4, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 317 | — | Q99986 |
| B | — | protein | 316 | — | Q99986 |
| C | — | protein | 307 | — | Q99986 |
| D | — | protein | 306 | — | Q99986 |
Ligands and binding sites
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 4 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 4 copies · chains A, B, C, D
- SO4 · Sulfate ion · ion · 7 copies · chains A, B, C, D
- CL · Chloride ion · ion · 4 copies · chains A, B, C, D
- PG4 · Tetraethylene glycol · additive · 2 copies · chains A, D, B
- GOL · Glycerol · additive · 2 copies · chains B, C, A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6AC9 · Crystal structure of human Vaccinia-related kinase 1 (VRK1) in complex with AMP-PNP · the same entry in another collection · chain D against D, TM-score 1.00
- Q99986 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase VRK1 (Q99986) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99986
- Elsewhere: RCSB PDB 6AC9 · PDBe 6AC9 · UniProt Q99986
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.