MolNFT v1 · #142585 · protein

Crystal structure of a apo form cyclase from fischerella sp.

6A8X · Aromatic prenyltransferase: “Crystal structure of a apo form cyclase from fischerella sp.”. X-ray diffraction, 1 ligand (CA), 6 pockets (best druggability 0.74). MolNFT v1 #142585 on GenesisL1: 3D structure, binding sites and…

PDB: 6A8X
Type: protein
Length: 406 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aromatic prenyltransferase
UniProt: A0A1L1VVY8
Ligands: CA
Pockets: 6 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Aromatic prenyltransferase	protein	203	0% helix, 43% strand	A0A1L1VVY8

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	259	0.74	0.87	27	empty
2	225	0.73	0.88	30	empty
3	117	0.68	0.90	29	empty
4	114	0.67	0.90	26	empty
5	197	0.44	0.74	32	empty

Interfaces

1 interface between chains.

A–B · 1137 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

6A8X · Crystal structure of a apo form cyclase from Fischerella sp. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1L1VVY8
Elsewhere: RCSB PDB 6A8X · PDBe 6A8X · UniProt A0A1L1VVY8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.