MolNFT v1 · #142550 · protein

Crystal structure of histone H2A.BBD-H2B dimer

6A7U · Histone H2B type 2-E,HISTONE H2A-bbd type 2/3: “Crystal structure of histone H2A.BBD-H2B dimer”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #142550 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6A7U
Type: protein
Length: 170 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Histone H2B type 2-E,HISTONE H2A-bbd type 2/3
UniProt: Q16778, P0C5Z0
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 69% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histone H2B type 2-E,HISTONE H2A-bbd type 2/3	protein	170	69% helix, 5% strand	Q16778, P0C5Z0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.29	0.74	16	empty

Compared structures

6A7U · Crystal structure of histone H2A.Bbd-H2B dimer · the same entry in another collection · chain A against A, TM-score 1.00
Q16778 · AlphaFold monomer V2.0 prediction for histone H2B type 2-E (Q16778) · a predicted model of the same protein · chain A against A, TM-score 0.49
P0C5Z0 · AlphaFold monomer V2.0 prediction for histone H2A-bbd type 2/3 (P0C5Z0) · a predicted model of the same protein · chain A against A, TM-score 0.47

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16778
Every structure of UniProt P0C5Z0
Elsewhere: RCSB PDB 6A7U · PDBe 6A7U · UniProt Q16778 · UniProt P0C5Z0

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