MolNFT v1 · #142529 · protein

Crystal structure of human ATP7B and tm complex

6A71 · ATP7B protein: “Crystal structure of human ATP7B and tm complex”. X-ray diffraction, 2 ligands (9UX, CA), 1 pocket (best druggability 0.31). MolNFT v1 #142529 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6A71
Type: protein
Length: 143 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP7B protein
UniProt: B7ZLR3
Ligands: 9UX, CA
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP7B protein	protein	72	31% helix, 32% strand	B7ZLR3
B	ATP7B protein	protein	71	31% helix, 32% strand	B7ZLR3

Ligands and binding sites

9UX · dioxo(di-mu-sulfide)dimolybdenum · ligand · chains B
CA · Calcium ion · metal · chains A, B
PEG · Di(hydroxyethyl)ether · additive · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.31	0.75	13	CA

Interfaces

1 interface between chains.

A–B · 346 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

6A71 · Crystal Structure of Human ATP7B and TM Complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B7ZLR3
Elsewhere: RCSB PDB 6A71 · PDBe 6A71 · UniProt B7ZLR3

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