MolNFT v1 · #142316 · protein
Cyclic alpha-maltosyl-(1-->6)-maltose hydrolase from arthrobacter globiformis, complex with panose
6A0K · Cyclic maltosyl-maltose hydrolase: “Cyclic alpha-maltosyl-(1-->6)-maltose hydrolase from arthrobacter globiformis, complex with panose”. X-ray diffraction, 3 ligands (GLC, BGC, CA), 3 pockets (best druggability 0.83). MolNFT v1…
- PDB
- 6A0K
- Type
- protein
- Length
- 892 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cyclic maltosyl-maltose hydrolase
- UniProt
- D2YYE1
- Ligands
- GLC, BGC, CA
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Cyclic maltosyl-maltose hydrolase | protein | 442 | 37% helix, 20% strand | D2YYE1 |
| A | Cyclic maltosyl-maltose hydrolase | protein | 450 | 37% helix, 19% strand | D2YYE1 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 10 copies · chains B, A
- BGC · beta-D-glucopyranose · sugar · 2 copies · chains B, A
- CA · Calcium ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 436 | 0.83 | 0.90 | 42 | empty |
| 2 | 152 | 0.44 | 0.76 | 18 | GLC |
| 3 | 136 | 0.43 | 0.76 | 25 | GLC |
Interfaces
1 interface between chains.
- B–A · 1156 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 6A0K · Cyclic alpha-maltosyl-(1-->6)-maltose hydrolase from Arthrobacter globiformis, complex… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D2YYE1
- Elsewhere: RCSB PDB 6A0K · PDBe 6A0K · UniProt D2YYE1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.