MolNFT v1 · #142116 · protein

The crystal structure of human DYRK2 in complex with curcumin

5ZTN: “The crystal structure of human DYRK2 in complex with curcumin”. X-ray diffraction, 1 ligand (CUR). MolNFT v1 #142116 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5ZTN
Type: protein
Length: 794 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q92630
Ligands: CUR

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	397	—	Q92630

Ligands and binding sites

CUR · (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5ZTN · The crystal structure of human DYRK2 in complex with Curcumin · the same entry in another collection · chain A against A, TM-score 1.00
Q92630 · AlphaFold monomer V2.0 prediction for dual specificity tyrosine… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92630
Elsewhere: RCSB PDB 5ZTN · PDBe 5ZTN · UniProt Q92630

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