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MolNFT v1 · #142015 · protein + DNA

Crystal structure of human topoisomerase II beta in complex with 5- iodouridine-containing-DNA in space group P3221

5ZQF: “Crystal structure of human topoisomerase II beta in complex with 5- iodouridine-containing-DNA in space group…”. X-ray diffraction, 1 ligand (MN). MolNFT v1 #142015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5ZQF
Type
protein + DNA
Length
725 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q02880
Ligands
MN

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein708—Q02880
B—dna8——
C—dna9——

Ligands and binding sites

  • MN · Manganese (II) ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5ZQF · Crystal structure of human topoisomerase II beta in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q02880 · AlphaFold monomer V2.0 prediction for DNA topoisomerase 2-beta (Q02880) · a predicted model of the same protein · chain A against A, TM-score 0.97

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