MolNFT v1 · #141963 · protein

Inward-facing conformation of L-ascorbate transporter ulaa

5ZOV · Pts ascorbate-specific subunit iibc: “Inward-facing conformation of L-ascorbate transporter ulaa”. X-ray diffraction, 2 ligands (ASC, CA), 16 pockets (best druggability 0.69). MolNFT v1 #141963 on GenesisL1: 3D structure, binding…

PDB: 5ZOV
Type: protein
Length: 798 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pts ascorbate-specific subunit iibc
UniProt: A0A1D7R1K6
Ligands: ASC, CA
Pockets: 16 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 75% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Pts ascorbate-specific subunit iibc	protein	399	75% helix, 5% strand	A0A1D7R1K6

Ligands and binding sites

ASC · Ascorbic acid · ligand · 2 copies · chains A, B
CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

16 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	421	0.69	0.81	51	empty
2	284	0.64	0.80	35	empty
3	159	0.58	0.81	21	empty
4	150	0.58	0.82	26	ASC
5	163	0.56	0.80	16	empty

Interfaces

1 interface between chains.

A–B · 896 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

5ZOV · Inward-facing conformation of L-ascorbate transporter UlaA · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1D7R1K6
Elsewhere: RCSB PDB 5ZOV · PDBe 5ZOV · UniProt A0A1D7R1K6

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