MolNFT v1 · #141870 · protein
Structure of neuc
5ZLR · GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing): “Structure of neuc”. X-ray diffraction, 2 ligands (LI, SO4), 7 pockets (best druggability 0.79). MolNFT v1 #141870 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5ZLR
- Type
- protein
- Length
- 736 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing)
- EC
- 3.2.1.184
- UniProt
- A0A154EJU5
- Ligands
- LI, SO4
- Pockets
- 7 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing) (EC 3.2.1.184) | protein | 370 | 43% helix, 15% strand | A0A154EJU5 |
| B | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing) (EC 3.2.1.184) | protein | 366 | 45% helix, 16% strand | A0A154EJU5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1192 | 0.79 | 0.81 | 85 | SO4 |
| 2 | 413 | 0.79 | 0.87 | 66 | SO4 |
| 3 | 145 | 0.59 | 0.83 | 34 | empty |
| 4 | 99 | 0.50 | 0.82 | 23 | empty |
| 5 | 86 | 0.49 | 0.82 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 2031 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 5ZLR · Structure of NeuC · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A154EJU5
- Elsewhere: RCSB PDB 5ZLR · PDBe 5ZLR · UniProt A0A154EJU5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.