MolNFT v1 · #14123 · protein

Glycosyltransferase B

1LZ7: “Glycosyltransferase B”. X-ray diffraction, 1 ligand (HG), 2 pockets (best druggability 0.55). MolNFT v1 #14123 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1LZ7
Type: protein
Length: 266 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyltransferase B
UniProt: P16442
Ligands: HG
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyltransferase B	protein	266	30% helix, 21% strand	P16442

Ligands and binding sites

HG · Mercury (II) ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	266	0.55	0.76	30	HG
2	63	0.31	0.75	16	empty

Compared structures

1LZ7 · Glycosyltransferase B · the same entry in another collection · chain A against A, TM-score 1.00
P16442 · AlphaFold monomer V2.0 prediction for histo-blood group abo system transferase (P16442) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P16442
Elsewhere: RCSB PDB 1LZ7 · PDBe 1LZ7 · UniProt P16442

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