MolNFT v1 · #141207 · protein

Crystal structure of P204 hinb domain

5YZW · IFI204: “Crystal structure of P204 hinb domain”. X-ray diffraction, 5 pockets (best druggability 0.78). MolNFT v1 #141207 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5YZW
Type: protein
Length: 384 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: IFI204
UniProt: A0A1Z3MI45
Pockets: 5 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	IFI204	protein	191	14% helix, 48% strand	A0A1Z3MI45
B	IFI204	protein	193	15% helix, 46% strand	A0A1Z3MI45

Pockets

5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	492	0.78	0.86	47	empty
2	270	0.69	0.84	27	empty
3	66	0.65	0.94	20	empty
4	154	0.61	0.84	18	empty
5	93	0.53	0.84	22	empty

Interfaces

1 interface between chains.

A–B · 829 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

5YZW · Crystal structure of p204 HINb domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1Z3MI45
Elsewhere: RCSB PDB 5YZW · PDBe 5YZW · UniProt A0A1Z3MI45

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