MolNFT v1 · #141179 · protein
Crystal structure of the MEK1 fha domain in complex with the HOP1 PTHR318 peptide.
5YYZ · Meiosis-specific SERINE/THREONINE-protein kinase MEK1: “Crystal structure of the MEK1 fha domain in complex with the HOP1 PTHR318 peptide.”. X-ray diffraction. MolNFT v1 #141179 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5YYZ
- Type
- protein
- Length
- 109 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Meiosis-specific SERINE/THREONINE-protein kinase MEK1; Meiosis-specific protein HOP1
- EC
- 2.7.11.1
- UniProt
- P24719, P20050
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Meiosis-specific SERINE/THREONINE-protein kinase MEK1 (EC 2.7.11.1) | protein | 102 | 0% helix, 44% strand | P24719 |
| B | Meiosis-specific protein HOP1 | protein | 7 | 0% helix, 0% strand | P20050 |
Interfaces
1 interface between chains.
- A–B · 381 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 5YYZ · Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. · the same entry in another collection · chain A against A, TM-score 1.00
- P24719 · AlphaFold monomer V2.0 prediction for meiosis-specific SERINE/THREONINE-protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.97
- P20050 · AlphaFold monomer V2.0 prediction for meiosis-specific protein HOP1 (P20050) · a predicted model of the same protein · chain B against A, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24719
- Every structure of UniProt P20050
- Elsewhere: RCSB PDB 5YYZ · PDBe 5YYZ · UniProt P24719 · UniProt P20050
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