Research workbench
Crystal structure of the MEK1 fha domain in complex with the HOP1 PTHR318 peptide.
Analyse Crystal structure of the MEK1 fha domain in complex with the HOP1 PTHR318… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5YYZ
- Type
- protein
- Length
- 109 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Meiosis-specific SERINE/THREONINE-protein kinase MEK1; Meiosis-specific protein HOP1
- EC
- 2.7.11.1
- UniProt
- P24719, P20050
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Meiosis-specific SERINE/THREONINE-protein kinase MEK1 (EC 2.7.11.1) | protein | 102 | 0% helix, 44% strand | P24719 |
| B | Meiosis-specific protein HOP1 | protein | 7 | 0% helix, 0% strand | P20050 |
Interfaces
1 interface between chains.
- A–B · 381 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 5YYZ · Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. · the same entry in another collection · chain A against A, TM-score 1.00
- P24719 · AlphaFold monomer V2.0 prediction for meiosis-specific SERINE/THREONINE-protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.97
- P20050 · AlphaFold monomer V2.0 prediction for meiosis-specific protein HOP1 (P20050) · a predicted model of the same protein · chain B against A, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24719
- Every structure of UniProt P20050
- Elsewhere: RCSB PDB 5YYZ · PDBe 5YYZ · UniProt P24719 · UniProt P20050
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