MolNFT v1 · #140670 · protein
Crystal structure of kni-10343 bound plasmepsin II (pmii) from plasmodium falciparum
5YIA: “Crystal structure of kni-10343 bound plasmepsin II (pmii) from plasmodium falciparum”. X-ray diffraction, 3 ligands (8V9, CPS, PO4). MolNFT v1 #140670 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YIA
- Type
- protein
- Length
- 328 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8I6V3
- Ligands
- 8V9, CPS, PO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 328 | — | Q8I6V3 |
Ligands and binding sites
- 8V9 · (4R)-3-[(2S,3S)-3-[[(2R)-2-[2-(4-hydroxyphenyl) ethanoylamino]-3-methylsulfanyl-propanoyl]amino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide · ligand · chains A
- CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
- GOL · Glycerol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YIA · Crystal Structure of KNI-10343 bound Plasmepsin II (PMII) from Plasmodium falciparum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8I6V3
- Elsewhere: RCSB PDB 5YIA · PDBe 5YIA · UniProt Q8I6V3
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