MolNFT v1 · #140651 · protein
Crystal structure of the anti-CRISPR protein, ACRF2
5YHR · Anti-CRISPR protein 30: “Crystal structure of the anti-CRISPR protein, ACRF2”. X-ray diffraction, 1 ligand (CA), 2 pockets (best druggability 0.32). MolNFT v1 #140651 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YHR
- Type
- protein
- Length
- 184 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anti-CRISPR protein 30
- UniProt
- Q6TM72
- Ligands
- CA
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Anti-CRISPR protein 30 | protein | 92 | 50% helix, 22% strand | Q6TM72 |
Ligands and binding sites
- CA · Calcium ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.32 | 0.73 | 19 | empty |
| 2 | 67 | 0.27 | 0.72 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1659 Ų buried · 31 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 5YHR · Crystal structure of the anti-CRISPR protein, AcrF2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6TM72
- Elsewhere: RCSB PDB 5YHR · PDBe 5YHR · UniProt Q6TM72
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