MolNFT v1 · #140645 · protein
Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist br-derivative
5YHL: “Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist…”. X-ray diffraction, 1 ligand (8VL). MolNFT v1 #140645 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YHL
- Type
- protein
- Length
- 717 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P35408
- Ligands
- 8VL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 280 | — | P35408 |
| H | — | protein | 223 | — | — |
| L | — | protein | 214 | — | — |
Ligands and binding sites
- 8VL · 4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl) propanoyl]amino]-4-cyano-phenyl]butanoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YHL · Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an… · the same entry in another collection · chain A against A, TM-score 1.00
- P35408 · AlphaFold monomer V2.0 prediction for prostaglandin E2 receptor EP4 subtype (P35408) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35408
- Elsewhere: RCSB PDB 5YHL · PDBe 5YHL · UniProt P35408
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