MolNFT v1 · #140617 · protein
Crystal structure of human fpps in complex with an inhibitor THZ93
5YGI: “Crystal structure of human fpps in complex with an inhibitor THZ93”. X-ray diffraction, 3 ligands (T93, MG, PO4). MolNFT v1 #140617 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YGI
- Type
- protein
- Length
- 338 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P14324
- Ligands
- T93, MG, PO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 338 | — | P14324 |
Ligands and binding sites
- T93 · [[(4-hexoxypyridin-2-yl)amino]-phosphono-methyl]phosphonic acid · ligand · chains A
- MG · Magnesium ion · metal · 3 copies · chains A
- PO4 · Phosphate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YGI · Crystal structure of human FPPS in complex with an inhibitor THZ93 · the same entry in another collection · chain A against A, TM-score 1.00
- P14324 · AlphaFold monomer V2.0 prediction for farnesyl pyrophosphate synthase (P14324) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14324
- Elsewhere: RCSB PDB 5YGI · PDBe 5YGI · UniProt P14324
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