MolNFT v1 · #140548 · protein
The crystal structure of lp-PLA2 in complex with a novel inhibitor
5YE8: “The crystal structure of lp-PLA2 in complex with a novel inhibitor”. X-ray diffraction, 1 ligand (8U3). MolNFT v1 #140548 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YE8
- Type
- protein
- Length
- 734 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13093
- Ligands
- 8U3
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 368 | — | Q13093 |
| A | — | protein | 366 | — | Q13093 |
Ligands and binding sites
- 8U3 · N-[3,4-bis(fluoranyl)phenyl]methanesulfonamide · ligand · 2 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YE8 · The crystal structure of Lp-PLA2 in complex with a novel inhibitor · the same entry in another collection · chain B against B, TM-score 1.00
- Q13093 · AlphaFold monomer V2.0 prediction for platelet-activating factor acetylhydrolase (Q13093) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13093
- Elsewhere: RCSB PDB 5YE8 · PDBe 5YE8 · UniProt Q13093
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