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MolNFT v1 · #140458 · protein

Crystal structure of the GLUA2O lbd in complex with glutamate and LY451395

5YBG: “Crystal structure of the GLUA2O lbd in complex with glutamate and LY451395”. X-ray diffraction, 2 ligands (8SO, ZN). MolNFT v1 #140458 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5YBG
Type
protein
Length
1,566 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P42262
Ligands
8SO, ZN

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, D, F—protein261—P42262
C—protein260—P42262
E—protein262—P42262

Ligands and binding sites

  • 8SO · N-[(2R)-2-[4-[4-[2-(methylsulfonylamino) ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide · ligand · 3 copies · chains A, B, C, D, E, F
  • ZN · Zinc ion · metal · 10 copies · chains A, C, B, D, E, F
  • ACT · Acetate ion · additive · 5 copies · chains A, C, D, E
  • GOL · Glycerol · additive · 2 copies · chains A, B, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5YBG · Crystal structure of the GluA2o LBD in complex with glutamate and LY451395 · the same entry in another collection · chain F against F, TM-score 1.00
  • P42262 · AlphaFold monomer V2.0 prediction for glutamate receptor 2 (P42262) · a predicted model of the same protein · chain E against A, TM-score 0.98

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