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MolNFT v1 · #140347 · protein

Complex structure of cyclin G-associated kinase with gefitinib

5Y80: “Complex structure of cyclin G-associated kinase with gefitinib”. X-ray diffraction, 1 ligand (IRE). MolNFT v1 #140347 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5Y80
Type
protein
Length
430 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
O14976
Ligands
IRE

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein306—O14976
B—protein124——

Ligands and binding sites

  • IRE · Gefitinib · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5Y80 · Complex structure of cyclin G-associated kinase with gefitinib · the same entry in another collection · chain A against A, TM-score 1.00
  • O14976 · AlphaFold monomer V2.0 prediction for cyclin-G-associated kinase (O14976) · a predicted model of the same protein · chain A against A, TM-score 0.98

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