UniProt O14976
O14976
O14976 (UniProt O14976): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14976
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
Structures
13 records of O14976 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C57 | Structure of GAK kinase in complex with a nanobody | x-ray diffraction | A, B | — | — |
| 4C57 | Structure of gak kinase in complex with a nanobody | x-ray diffraction | A, B | — | — |
| 4C58 | Structure of GAK kinase in complex with nanobody (NbGAK_4) | x-ray diffraction | A | — | — |
| 4C58 | Structure of gak kinase in complex with nanobody (NBGAK_4) | x-ray diffraction | A | — | — |
| 4C59 | Structure of GAK kinase in complex with nanobody (NbGAK_4) | x-ray diffraction | A | — | — |
| 4C59 | Structure of gak kinase in complex with nanobody (NBGAK_4) | x-ray diffraction | A | — | — |
| 4O38 | Crystal structure of the human cyclin G associated kinase (GAK) | x-ray diffraction | A, B | — | — |
| 4O38 | Crystal structure of the human cyclin G associated kinase (gak) | x-ray diffraction | A, B | — | — |
| 4Y8D | Crystal structure of Cyclin-G associated kinase (GAK) complexed with selective 12i inhibitor | x-ray diffraction | A, B | — | — |
| 4Y8D | Crystal structure of cyclin-G associated kinase (gak) complexed with selective 12I inhibitor | x-ray diffraction | A, B | — | — |
| 5Y7Z | Complex structure of cyclin G-associated kinase with gefitinib | x-ray diffraction | A, B | IRE, SO4 | — |
| 5Y80 | Complex structure of cyclin G-associated kinase with gefitinib | x-ray diffraction | A | IRE | — |
| O14976 | AlphaFold monomer V2.0 prediction for cyclin-G-associated kinase (O14976) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5Y7Z chain A against the predicted model O14976: TM-score 0.99, RMSD 0.50 Å
- 5Y7Z chain B against the predicted model O14976: TM-score 0.99, RMSD 0.57 Å
- 4C57 chain A against the predicted model O14976: TM-score 0.99, RMSD 0.73 Å
- 4C57 chain A against the predicted model O14976: TM-score 0.99, RMSD 0.73 Å
- 4C57 chain B against the predicted model O14976: TM-score 0.99, RMSD 0.80 Å
- 4C57 chain B against the predicted model O14976: TM-score 0.99, RMSD 0.80 Å
- 5Y80 chain A against the predicted model O14976: TM-score 0.98, RMSD 0.95 Å
- 4Y8D chain A against the predicted model O14976: TM-score 0.95, RMSD 1.35 Å
- 4Y8D chain A against the predicted model O14976: TM-score 0.95, RMSD 1.35 Å
- 4Y8D chain B against the predicted model O14976: TM-score 0.95, RMSD 1.37 Å
Elsewhere
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