MolNFT v1 · #140285 · protein
Crystal structures of spleen tyrosine kinase in complex with a novel inhibitor
5Y5T: “Crystal structures of spleen tyrosine kinase in complex with a novel inhibitor”. X-ray diffraction, 1 ligand (8OR). MolNFT v1 #140285 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5Y5T
- Type
- protein
- Length
- 263 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P43405
- Ligands
- 8OR
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 263 | — | P43405 |
Ligands and binding sites
- 8OR · 2-[[(1S,2S)-2-azanylcyclohexyl]amino]-4-[(4-methylsulfonylphenyl)amino]-6H-pyrido[4,3-d]pyrimidin-5-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5Y5T · Crystal structures of spleen tyrosine kinase in complex with a novel inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43405
- Elsewhere: RCSB PDB 5Y5T · PDBe 5Y5T · UniProt P43405
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