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MolNFT v1 · #140251 · protein

Crystal structure of trypanosoma cruzi spermidine synthase in complex with 5-methoxy-2-(5-methyl-4,5-dihydro-1H-imidazol-2-YL)PHENOL

5Y4P: “Crystal structure of trypanosoma cruzi spermidine synthase in complex with…”. X-ray diffraction, 2 ligands (S4M, 8QO). MolNFT v1 #140251 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5Y4P
Type
protein
Length
1,091 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q4DA73
Ligands
S4M, 8QO

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein266—Q4DA73
B—protein278—Q4DA73
C—protein273—Q4DA73
D—protein274—Q4DA73

Ligands and binding sites

  • S4M · 5'-[(S)-(3-aminopropyl)(methyl)-lambda~4~-sulfanyl]-5'-deoxyadenosine · ligand · 4 copies · chains A, B, C, D
  • 8QO · 5-methoxy-2-[(5R)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]phenol · ligand · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5Y4P · Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

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