UniProt Q4DA73
Spermidine synthase, putative (Q4DA73)
Spermidine synthase, putative (UniProt Q4DA73), EC 2.5.1.16: 26 experimental structures on GenesisL1, 12 ligands bound, 76 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4DA73
- Protein
- Spermidine synthase, putative
- EC
- 2.5.1.16
- Experimental structures
- 26
- Predicted models
- 0
- Ligands
- 12
- Pockets
- 76 · 13 records with a druggable one
Structures
26 records of Q4DA73 in the MolNFT archive: 26 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BWB | Crystal structure of the apo form of spermidine synthase from Trypanosoma cruzi at 2.5 A resolution | x-ray diffraction | A, B | — | 3 (best 0.77) |
| 3BWB | Crystal structure of the apo form of spermidine synthase from trypanosoma cruzi at 2.5 a resolution | x-ray diffraction | A, B | — | — |
| 3BWC | Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A… | x-ray diffraction | A, B | SAM | 3 (best 0.70) |
| 3BWC | Crystal structure of spermidine synthase from trypanosoma cruzi in complex with SAM at 2.3 a… | x-ray diffraction | A, B | — | — |
| 4YUV | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with decarboxylated… | x-ray diffraction | A, B | S4M | 4 (best 0.78) |
| 4YUV | Crystal structure of trypanosoma cruzi spermidine synthase in complex with decarboxylated… | x-ray diffraction | A, B | — | — |
| 4YUW | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | S4M, 4JU | 4 (best 0.79) |
| 4YUW | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | — | — |
| 4YUX | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | S4M, 4JT | 5 (best 0.80) |
| 4YUX | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | — | — |
| 4YUY | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with isoquinolin-1-amine | x-ray diffraction | A, B | S4M, 1SQ | 4 (best 0.81) |
| 4YUY | Crystal structure of trypanosoma cruzi spermidine synthase in complex with isoquinolin-1-amine | x-ray diffraction | A, B | — | — |
| 4YUZ | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 4JV | 7 (best 0.83) |
| 4YUZ | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4YV0 | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 4JW | 10 (best 0.80) |
| 4YV0 | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 4YV1 | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with quinolin-8-yl… | x-ray diffraction | A, B, C, D | S4M, 4K2 | 6 (best 0.86) |
| 4YV1 | Crystal structure of trypanosoma cruzi spermidine synthase in complex with quinolin-8-yl… | x-ray diffraction | A, B, C, D | — | — |
| 4YV2 | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | S4M, 4K3 | 3 (best 0.83) |
| 4YV2 | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B | — | — |
| 5B1S | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, BSX | 9 (best 0.80) |
| 5B1S | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 5Y4P | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 8QO | 8 (best 0.78) |
| 5Y4P | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 8QO | — |
| 5Y4Q | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 8OF | 10 (best 0.81) |
| 5Y4Q | Crystal structure of trypanosoma cruzi spermidine synthase in complex with… | x-ray diffraction | A, B, C, D | S4M, 8OF | — |
Ligands
- S4M · 5'-[(S)-(3-aminopropyl)(methyl)-lambda~4~-sulfanyl]-5'-deoxyadenosine · in 13 records
- 8OF · N-(4-methoxyphenyl)quinolin-4-amine · in 2 records
- 8QO · 5-methoxy-2-[(5R)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]phenol · in 2 records
- 1SQ · Isoquinolin-1-amine · in 1 record
- 4JT · 2H-1,4-benzothiazin-3-amine · in 1 record
- 4JU · trans-4-methylcyclohexanamine · in 1 record
- 4JV · 5-[(4-methylbenzyl)oxy]quinazoline-2,4-diamine · in 1 record
- 4JW · (2S)-N-methyl-N-phenyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide · in 1 record
- 4K2 · quinolin-8-yl piperidine-1-carboxylate · in 1 record
- 4K3 · N-phenyl-3-sulfanylpropanamide · in 1 record
- BSX · 2-(2-fluorophenyl)ethanamine · in 1 record
- SAM · S-adenosylmethionine · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.