MolNFT v1 · #140205 · protein + DNA + RNA
Cryo-EM structure of SPCAS9-sgrna-DNA ternary complex
5Y36: “Cryo-EM structure of SPCAS9-sgrna-DNA ternary complex”. Electron microscopy, 1 ligand (MG). MolNFT v1 #140205 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5Y36
- Type
- protein + DNA + RNA
- Length
- 1,549 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q99ZW2
- Ligands
- MG
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1368 | — | Q99ZW2 |
| B | — | rna | 99 | — | — |
| C | — | dna | 41 | — | — |
| D | — | dna | 41 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5Y36 · Cryo-EM structure of SpCas9-sgRNA-DNA ternary complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q99ZW2 · AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9/CSN1 (Q99ZW2) · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99ZW2
- Elsewhere: RCSB PDB 5Y36 · PDBe 5Y36 · UniProt Q99ZW2
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