MolNFT v1 · #13999 · protein

Full matrix error analysis of streptavidin

1LUQ: “Full matrix error analysis of streptavidin”. X-ray diffraction, 1 ligand (BTN), 2 pockets (best druggability 0.50). MolNFT v1 #13999 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1LUQ
Type: protein
Length: 239 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Streptavidin
Ligands: BTN
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Streptavidin	protein	119	5% helix, 58% strand	—
B	Streptavidin	protein	120	5% helix, 57% strand	—

Ligands and binding sites

BTN · Biotin · ligand · 2 copies · chains A, B
GOL · Glycerol · additive · chains A, B
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.50	0.82	19	BTN
2	96	0.50	0.82	18	BTN

Interfaces

1 interface between chains.

A–B · 1610 Å² buried · 32 hydrogen bonds · protein-protein

Compared structures

1LUQ · Full Matrix Error Analysis of Streptavidin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1LUQ · PDBe 1LUQ

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