MolNFT v1 · #139950 · protein
Crystal structure of PAK4 in complex with inhibitor CZH216
5XVA: “Crystal structure of PAK4 in complex with inhibitor CZH216”. X-ray diffraction, 1 ligand (8FU). MolNFT v1 #139950 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5XVA
- Type
- protein
- Length
- 293 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O96013
- Ligands
- 8FU
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 293 | — | O96013 |
Ligands and binding sites
- 8FU · [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl) amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone · ligand · chains A
- EOH · Ethanol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5XVA · Crystal Structure of PAK4 in complex with inhibitor CZH216 · the same entry in another collection · chain A against A, TM-score 1.00
- O96013 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 4 (O96013) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O96013
- Elsewhere: RCSB PDB 5XVA · PDBe 5XVA · UniProt O96013
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