MolNFT v1 · #139946 · protein
Crystal structure of ATG101-ATG13HORMA
5XV6 · Autophagy-related protein 13: “Crystal structure of ATG101-ATG13HORMA”. X-ray diffraction, 3 pockets (best druggability 0.61). MolNFT v1 #139946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5XV6
- Type
- protein
- Length
- 399 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autophagy-related protein 13; Autophagy-related protein 101
- UniProt
- O75143, Q9BSB4
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autophagy-related protein 13 | protein | 185 | 38% helix, 29% strand | O75143 |
| B | Autophagy-related protein 101 | protein | 214 | 35% helix, 32% strand | Q9BSB4 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 222 | 0.61 | 0.81 | 29 | empty |
| 2 | 98 | 0.38 | 0.76 | 20 | empty |
| 3 | 68 | 0.29 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1374 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 5XV6 · Crystal structure of ATG101-ATG13HORMA · the same entry in another collection · chain A against A, TM-score 1.00
- O75143 · AlphaFold monomer V2.0 prediction for autophagy-related protein 13 (O75143) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q9BSB4 · AlphaFold monomer V2.0 prediction for autophagy-related protein 101 (Q9BSB4) · a predicted model of the same protein · chain B against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75143
- Every structure of UniProt Q9BSB4
- Elsewhere: RCSB PDB 5XV6 · PDBe 5XV6 · UniProt O75143 · UniProt Q9BSB4
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