UniProt O75143
Autophagy-related protein 13 (O75143)
Autophagy-related protein 13 (UniProt O75143): 24 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75143
- Protein
- Autophagy-related protein 13
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 53 · 9 records with a druggable one
Structures
25 records of O75143 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WAN | Crystal structure of Atg13 LIR-fused human LC3A_2-121 | x-ray diffraction | A, B | — | — |
| 3WAN | Crystal structure of ATG13 lir-fused human LC3A_2-121 | x-ray diffraction | A, B | — | — |
| 3WAO | Crystal structure of Atg13 LIR-fused human LC3B_2-119 | x-ray diffraction | A, B, C, D | — | — |
| 3WAO | Crystal structure of ATG13 lir-fused human LC3B_2-119 | x-ray diffraction | A, B, C, D | — | — |
| 3WAP | Crystal structure of Atg13 LIR-fused human LC3C_8-125 | x-ray diffraction | A | — | — |
| 3WAP | Crystal structure of ATG13 lir-fused human LC3C_8-125 | x-ray diffraction | A | — | — |
| 5C50 | Crystal structure of the complex of human Atg101-Atg13 HORMA domain | x-ray diffraction | B | BEN | 3 (best 0.52) |
| 5C50 | Crystal structure of the complex of human ATG101-ATG13 horma domain | x-ray diffraction | B | — | — |
| 5XUY | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | 4 (best 0.74) |
| 5XUY | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | — |
| 5XV1 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | 5 (best 0.68) |
| 5XV1 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | — |
| 5XV3 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | — |
| 5XV3 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C | — | — |
| 5XV4 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C, E, G, I, K, M, O | — | 20 (best 0.80) |
| 5XV4 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A, C, E, G, I, K, M, O | — | — |
| 5XV6 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A | — | 3 (best 0.61) |
| 5XV6 | Crystal structure of ATG101-ATG13HORMA | x-ray diffraction | A | — | — |
| 6HYN | Structure of ATG13 LIR motif bound to GABARAP | x-ray diffraction | A | — | — |
| 6HYN | Structure of ATG13 lir motif bound to gabarap | x-ray diffraction | A | — | — |
| 8DO8 | Crystal structure ATG9 HDIR in complex with the ATG13:ATG101 HORMA dimer | x-ray diffraction | B, D | — | 5 (best 0.67) |
| 8SOI | Structure of human ULK1 complex core (2:1:1 stoichiometry) | electron microscopy | D | — | 2 (best 0.79) |
| 8SQZ | Structure of human ULK1 complex core (2:2:2 stoichiometry) in the PI3KC3-C1 mixture | electron microscopy | E, F | — | 5 (best 0.78) |
| 8SRM | Structure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant | electron microscopy | E, F | — | 6 (best 0.80) |
| O75143 | AlphaFold monomer V2.0 prediction for autophagy-related protein 13 (O75143) | predicted | A | — | — |
Ligands
- BEN · Benzamidine · in 1 record
Experiment against prediction
- 5XV1 chain C against the predicted model O75143: TM-score 0.99, RMSD 0.49 Å
- 5XV1 chain C against the predicted model O75143: TM-score 0.99, RMSD 0.49 Å
- 5XUY chain C against the predicted model O75143: TM-score 0.99, RMSD 0.52 Å
- 5XUY chain C against the predicted model O75143: TM-score 0.99, RMSD 0.52 Å
- 5XV4 chain K against the predicted model O75143: TM-score 0.99, RMSD 0.55 Å
- 5XV4 chain K against the predicted model O75143: TM-score 0.99, RMSD 0.55 Å
- 5XV4 chain E against the predicted model O75143: TM-score 0.99, RMSD 0.56 Å
- 5XV4 chain E against the predicted model O75143: TM-score 0.99, RMSD 0.56 Å
- 5XV4 chain G against the predicted model O75143: TM-score 0.99, RMSD 0.57 Å
- 5XV4 chain G against the predicted model O75143: TM-score 0.99, RMSD 0.57 Å
Elsewhere
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