MolNFT v1 · #139922 · protein
Crystal structure of PDE10A in complex with 2-methyl-5-[2-([1,2, 4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)ET HYL]PYRAZOLO[1,5-A]PYRIMIDIN-7-ol
5XUI: “Crystal structure of PDE10A in complex with 2-methyl-5-[2-([1,2, 4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)ET…”. X-ray diffraction, 3 ligands (8G3, ZN, MG). MolNFT v1 #139922 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5XUI
- Type
- protein
- Length
- 644 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y233
- Ligands
- 8G3, ZN, MG
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 322 | — | Q9Y233 |
Ligands and binding sites
- 8G3 · 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl) ethyl]pyrazolo[1,5-a]pyrimidin-7-ol · ligand · chains A
- ZN · Zinc ion · metal · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5XUI · Crystal structure of PDE10A in complex with 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y233
- Elsewhere: RCSB PDB 5XUI · PDBe 5XUI · UniProt Q9Y233
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