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MolNFT v1 · #139776 · protein

Crystal structure of MAD2L2/REV7 in complex with a camp fragment in a tetragonal crystal

5XPT · Mitotic spindle assembly checkpoint protein MAD2B: “Crystal structure of MAD2L2/REV7 in complex with a camp fragment in a tetragonal crystal”. X-ray diffraction. MolNFT v1 #139776 on GenesisL1: 3D structure, binding sites and…

PDB
5XPT
Type
protein
Length
210 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Mitotic spindle assembly checkpoint protein MAD2B; Chromosome alignment-maintaining…
UniProt
Q9UI95, Q96JM3

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMitotic spindle assembly checkpoint protein MAD2Bprotein19735% helix, 31% strandQ9UI95
BChromosome alignment-maintaining phosphoprotein 1protein130% helix, 23% strandQ96JM3

Interfaces

1 interface between chains.

  • A–B · 919 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

  • 5XPT · Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9UI95 · AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2B… · a predicted model of the same protein · chain A against A, TM-score 0.90
  • Q96JM3 · AlphaFold monomer V2.0 prediction for chromosome alignment- maintaining phosphoprotein 1… · a predicted model of the same protein · chain B against A, TM-score 0.31

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