MolNFT v1 · #139729 · protein
Crystal structure of the apo staphylococcus aureus phosphofructokinase
5XOE · ATP-dependent 6-phosphofructokinase: “Crystal structure of the apo staphylococcus aureus phosphofructokinase”. X-ray diffraction, 2 pockets (best druggability 0.54). MolNFT v1 #139729 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5XOE
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP-dependent 6-phosphofructokinase
- EC
- 2.7.1.11
- UniProt
- Q2FXM8
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent 6-phosphofructokinase (EC 2.7.1.11) | protein | 318 | 44% helix, 18% strand | Q2FXM8 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 231 | 0.54 | 0.77 | 34 | empty |
| 2 | 94 | 0.33 | 0.73 | 19 | empty |
Compared structures
- 5XOE · Crystal Structure of the apo Staphylococcus aureus phosphofructokinase · the same entry in another collection · chain A against A, TM-score 1.00
- Q2FXM8 · AlphaFold monomer V2.0 prediction for ATP-dependent 6-phosphofructokinase (Q2FXM8) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2FXM8
- Elsewhere: RCSB PDB 5XOE · PDBe 5XOE · UniProt Q2FXM8
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