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Crystal structure of the apo staphylococcus aureus phosphofructokinase

Analyse Crystal structure of the apo staphylococcus aureus phosphofructokinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5XOE
Type: protein
Length: 318 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP-dependent 6-phosphofructokinase
EC: 2.7.1.11
UniProt: Q2FXM8
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-dependent 6-phosphofructokinase (EC 2.7.1.11)	protein	318	44% helix, 18% strand	Q2FXM8

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	231	0.54	0.77	34	empty
2	94	0.33	0.73	19	empty

Compared structures

5XOE · Crystal Structure of the apo Staphylococcus aureus phosphofructokinase · the same entry in another collection · chain A against A, TM-score 1.00
Q2FXM8 · AlphaFold monomer V2.0 prediction for ATP-dependent 6-phosphofructokinase (Q2FXM8) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2FXM8
Elsewhere: RCSB PDB 5XOE · PDBe 5XOE · UniProt Q2FXM8

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