MolNFT v1 · #139715 · protein
Crystal structure of the isochorismatase domain of angb from vibrio anguillarum 775
5XO0 · Ischorismate lyase: “Crystal structure of the isochorismatase domain of angb from vibrio anguillarum 775”. X-ray diffraction, 4 pockets (best druggability 0.75). MolNFT v1 #139715 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5XO0
- Type
- protein
- Length
- 418 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ischorismate lyase
- UniProt
- Q6W4P9
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ischorismate lyase | protein | 209 | 38% helix, 19% strand | Q6W4P9 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.75 | 0.96 | 20 | empty |
| 2 | 92 | 0.74 | 0.96 | 20 | empty |
| 3 | 218 | 0.56 | 0.79 | 19 | empty |
| 4 | 55 | 0.28 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1474 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 5XO0 · Crystal structure of the isochorismatase domain of AngB from Vibrio anguillarum 775 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6W4P9
- Elsewhere: RCSB PDB 5XO0 · PDBe 5XO0 · UniProt Q6W4P9
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