MolNFT v1 · #139059 · protein
The Y81G mutant of the ung crystal structure from nitratifractor salsuginis
5X3H · Uracil-DNA glycosylase: “The Y81G mutant of the ung crystal structure from nitratifractor salsuginis”. X-ray diffraction, 5 pockets (best druggability 0.59). MolNFT v1 #139059 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5X3H
- Type
- protein
- Length
- 495 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uracil-DNA glycosylase
- UniProt
- E6WYZ8
- Pockets
- 5 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uracil-DNA glycosylase | protein | 246 | 46% helix, 12% strand | E6WYZ8 |
| B | Uracil-DNA glycosylase | protein | 249 | 47% helix, 12% strand | E6WYZ8 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.59 | 0.80 | 33 | empty |
| 2 | 240 | 0.54 | 0.77 | 30 | empty |
| 3 | 221 | 0.53 | 0.77 | 26 | empty |
| 4 | 141 | 0.52 | 0.80 | 33 | empty |
| 5 | 96 | 0.43 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 647 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 5X3H · The Y81G mutant of the UNG crystal structure from Nitratifractor salsuginis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E6WYZ8
- Elsewhere: RCSB PDB 5X3H · PDBe 5X3H · UniProt E6WYZ8
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