Research workbench

The Y81G mutant of the ung crystal structure from nitratifractor salsuginis

Analyse The Y81G mutant of the ung crystal structure from nitratifractor salsuginis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5X3H
Type: protein
Length: 495 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uracil-DNA glycosylase
UniProt: E6WYZ8
Pockets: 5 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uracil-DNA glycosylase	protein	246	46% helix, 12% strand	E6WYZ8
B	Uracil-DNA glycosylase	protein	249	47% helix, 12% strand	E6WYZ8

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	227	0.59	0.80	33	empty
2	240	0.54	0.77	30	empty
3	221	0.53	0.77	26	empty
4	141	0.52	0.80	33	empty
5	96	0.43	0.79	20	empty

Interfaces

1 interface between chains.

A–B · 647 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5X3H · The Y81G mutant of the UNG crystal structure from Nitratifractor salsuginis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E6WYZ8
Elsewhere: RCSB PDB 5X3H · PDBe 5X3H · UniProt E6WYZ8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.